Clinical Trials

Inotek has sponsored Phase 1, Phase 2 and Phase 3 clinical trials for trabodenoson monotherapy which have concluded, as well as a Phase 2 clinical trial for trabodenoson + latanoprost in a fixed-dose combination. Click the links below to learn more about each trial through clinicaltrials.gov.

IdentifierStatusTherapyStudy Name
NCT02829996CompletedFixed-dose combinationStudy of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma
NCT02565173CompletedTrabodenoson monotherapyStudy of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma
NCT01917383CompletedTrabodenoson monotherapyA Phase II Study to Evaluate the Additivity of Trabodenoson to Latanoprost in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma
NCT01123785CompletedTrabodenoson monotherapyA Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of INO-8875 in Adults With Ocular Hypertension or Primary Open-Angle Glaucoma
NCT01123772CompletedTrabodenoson monotherapyPhase I Dose-Escalation Study to Evaluate Tolerability, Safety & PK of INO-8875 in Healthy Older-Adult Volunteers